gms | German Medical Science

21st Annual Meeting of the German Retina Society and 8th Symposium of the International Society of Ocular Trauma (ISOT)

German Retina Society
International Society of Ocular Trauma

19.06. - 22.06.2008, Würzburg

Prophylaxis of proliferative vitreoretinopathy by early vitrectomy in severe ocular trauma: preliminary results of a multicenter prospective study

Meeting Abstract

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  • Wolfgang F. Schrader - Würzburg/Germany
  • D. Pröll - Würzburg/Germany
  • L. Mann - Birmingham/USA
  • F. Kuhn - Birmingham/USA

Retinologische Gesellschaft. International Society of Ocular Trauma. 21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem 8. Symposium der International Society of Ocular Trauma. Würzburg, 19.-22.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocISOTRG2008V039b

The electronic version of this article is the complete one and can be found online at:

Published: June 18, 2008

© 2008 Schrader et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Background: In spite of the progress in vitreoretinal surgery, the anatomical and functional results of severe ocular injuries involving the posterior segment are still discouraging. Perforating injuries and ruptures, that extend posterior to the muscle insertions, have the worst outcome. At the time of secondary intervention between day 7 and 14 post trauma it is not unlikely that severe PVR already occurred. The authors present the preliminary results of an ongoing prospective international trial on severe ocular ruptures and perforating injuries (with entrance and exit wounds, with at least one wound behind the insertion of the rectus muscles), with the posterior segment reconstruction performed already within 100 hours following the trauma.

Method: 6 centers contributed to the preliminary results of the ongoing multicenter prospective trial “Proactive Management of Eyes with Perforating/Rupture/IOFB Injuries".

Results: Among the cases, that were contributed for the study, anatomic and functional results seem to be better with this new approach than with the conventional technique. More than 50% of the cases reached a visual acuity of 0.1 or better, none became completely blind (NLP), or developed a phthisis or had to be enucleated.

Conclusion: Based on a new approach to act rather than to react on alterations secondary to severe posterior segment trauma the functional results of these injuries may be further improved. The prospective multicenter multinational study conducted by the World Eye Injury Register will be continued.