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33rd International Congress on Electrocardiology

International Society of Electrocardiology

Variability of vegetative regulation of childhood cardiac rhythm during high altitude adaptation

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33rd International Congress on Electrocardiology. Cologne, 28.06.-01.07.2006. Düsseldorf, Köln: German Medical Science; 2007. Doc06ice145

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Published: February 8, 2007

© 2007 Makimbetova.
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Objectives: The aim of this study was to ascertain the influence of high altitude, age and gender on the heart rate variability parameters and age peculiarities of vegetative regulation in children.

Material and methods: There were observed 280 residents (school age) of high altitude (Naryn, 2800 m) areas. Rhythmography was registered by automatic and analogy digital system. All subjects were examined under standard conditions and during active orthostatic testing. Analyzed: dRR, ms – R-R interval in horizontal position (RR1), RRb, ms – minimal interval during standing, dRRb – maximal reaction of heart rhythm during orthotest, dRRb, %– in percents, RRc, ms – interval during decreasing of reflection after standing, Таb, с – the time of speed up during standing, Тас, s – the time between beginning of standing and maximal decreasing heart rhythm, Та1b1, s – the time of heart rhythm recovery, total spectral power.

Results: In boys the length of the R-R interval has prolonged significantly with age. In male of high altitude two fold increasing of the classes of rhythmograms with normal and adequate reaction on orthotest was demonstrated as compared to parameters of low altitude residents. Spectral analyses showed that in children of high altitude areas the parasympathetic influence on the heart rhythm was more stronger than in low altitude residents. During the first stage of orthotest the spectral power of sympathetic and hormonal systems in male residents of low altitude was significantly higher than in compared group. On the second stage (standing) we showed the expressive parasympathetic influence on the heart rhythm in boys residents of high altitude. However in age group (15-17 years) from low and high altitude the sympathetic tonus of vegetative nervous system had the similar parameters. The girls, residents of high altitude, especially in youngest age group, had longer R-R interval, higher dispersion of heart rhythm and amplitude of breath arrhythmia, lower arterial blood pressure than similar comparing group during all stages of orthotest.

Conclusion: The intensification of reflective parasympathetic influence on cardiac rhythm occurs during growing up and is more marked in high altitude residents. Year analysis reveals an essential reduction of heart rate, increase of the levels of systolic and diastolic pressures.