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29. Wissenschaftlicher Kongress der Deutschen Hochdruckliga

Deutsche Hochdruckliga e. V. DHL ® - Deutsche Hypertonie Gesellschaft Deutsches Kompetenzzentrum Bluthochdruck

23. bis 25.11.2005, Berlin

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The Influence Of Body Weight And Blood Pressure Response To Exercise On Cardiac Alterations In Patients With Normotensive ABPM Va

Die Bedeutung von Körpergewicht und Blutdruck während Ergometrie für kardiale Anpassungen bei Patienten mit normotensiver ABDM

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  • J. Müller - Klinik Wehrawald der BfA Todtmoos (Todtmoos, D)
  • I.W. Franz - Klinik Wehrawald der BfA Todtmoos (Todtmoos, D)

Hypertonie 2005. 29. Wissenschaftlicher Kongress der Deutschen Hochdruckliga. Berlin, 23.-25.11.2005. Düsseldorf, Köln: German Medical Science; 2006. Doc05hochP42

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/hoch2005/05hoch042.shtml

Published: August 8, 2006

© 2006 Müller et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

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Background: Exercise blood pressure (ExBP) and BMI have an impact on cardiac alterations and therefore also an influence on cardiovascular morbitity and mortality. But it is unclear which of these parameters is of greater influence.

Methods: Out of 1466 patients a group of 557 (f: 317, m: 240, age: 48.7±11.7y.) was identified as normotensives after ABPM (daytime<135/<85mmHg, SpaceLabs 90207). All patients underwent standardized ergometry (50-100watts, 5 min recovery period), echocardiography and were finally arbitrarily divided into 3 groups according to their BMI (table 1 [Tab. 1]).

Results: Despite clear normotensive BP values during ABPM and comparable heart rates, ExBP has a great impact on cardiac alterations (LVMI, LA size, E/A ratio). This effect is more pronounced (G1ExBP-: G1ExBP+ = p<0.001; G2ExBP-: G2ExBP+ = p<0.001; G3ExBP-: G3ExBP+ = p<0.001) than the influence of BMI (G1ExBP-: G2ExBP-: G3ExBP- = n.s. and G1ExBP+: G2ExBP+: G3ExBP+ = n.s.).

Conclusions: Patients with normotensive blood pressure values during ABPM and increased exercise blood pressure showed typical hypertensive adaptations of the heart and this effect is significantly more pronounced (p< 0.001) than the influence of BMI.