Article
Einfluss des Körpergewichtes auf den Blutdruck während Ergometrie bei Patienten mit normotensiver ABDM
The Influence Of Body Weight On Blood Pressure Response To Exercise In Patients With Normotensive ABPM Values
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Published: | November 11, 2004 |
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Outline
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Background
A hypertensive blood pressure (BP) response is known as a more reliable predictor for LVH and cardiovascular mortality compared to casual BP. Obese patients have an increased cardiovascular risk. One reason could be a hypertensive BP response only during exercise.
Methods
1466 persons underwent an ABPM and a group of 557 (f: 317, m: 240, age: 48.7±11.7y.) was identified as normotensive (daytime=135/=85mmHg, SpaceLabs 90207). All patients underwent standardized ergometry (50-100watts, 5 min recovery period), echocardiography and were finally arbitrarily divided into 3 groups according to their BMI [Tab. 1].
Results
Despite clear normotensive BP values during ABPM and comparable heart rates, the percentage of patients with a hypertensive BP response during ergometry (ExBP+, >200/>100 mmHg at 100 watts) increased significantly (p<0.001) according to their increased BMI and was accompanied by a significantly (p<0.01 - p<0.001) higher LVMI compared to patients with normal exercise BP (ExBP-).
Patients with increased ExBP showed significantly higher (p<0.05 - 0.001) ldl-cholesterol and triglyceride levels and significantly lower hdl-cholesterol levels.
Conclusions
Despite normotensive BP during ABPM, obese patients frequently show a pathologically increased BP response during standardized ergometry. This increased BP response to exercise has an influence not only on LVMI, but also on cardiovascular mortality, and should therefore be assessed in obese patients.