gms | German Medical Science

83rd Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

16.05. - 20.05.2012, Mainz

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To restore eye blink and eyelid closure of denervated orbicularis oculi muscle with “artificial facial nerve reflex”

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  • corresponding author Keyong Li - Shanghai JiaoTong University affiliated first people's hospital, Shanghai, P.R.China
  • Jingquan Liu - Micro-nano technology laboratory of Shanghai JiaoTong University, Shanghai, P.R.China
  • Dongyue Xu - Shanghai JiaoTong University affiliated first people's hospital, Shanghai, P.R.China
  • Yuefeng Rui - Micro-nano technology laboratory of Shanghai JiaoTong University, Shanghai, P.R.China

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 83. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Mainz, 16.-20.05.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12hnod726

doi: 10.3205/12hnod726, urn:nbn:de:0183-12hnod7268

Published: April 4, 2012

© 2012 Li et al.
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Objective： To restore function and facial expression of injured facial muscle in peripheral facial paralysis patients with “artificial facial nerve reflex”.

Method: 12 rabbits were used as animal model with peripheral facial paralysis. An artificial facial nerve reflex on the animal models was established by implanted recording, stimulating electrodes and outer computer. Recording electrodes employed as efferent nerve and stimulating electrodes as afferent nerve. Outer computer, which employed as central nerve system, received EMG’s signal from health orbicularis oculi muscle (OOM), recognized the acting states of OMM according to EMG, then switched on the stimulator and outputted the electric current to stimulate directly injured OMM, So that the injured OMM without facial nerve can contract following up the health OMM. We tested and compare the threshold electrical intensity witch could just close eye in 7th day with one in 28th day 30 times. We count the number of uninjured eyelid closure and corresponding the number of uninjured EMG above threshold , the number of releasing electrical stimulating and the number of injured eyelid closure.

Result: The optimal electrical intensity was 0.30mA at 60Hz. The threshold electrical intensity in 7th day and in 28th day had no difference using SPSS analysis. And in the whole artificial reflex, most of reflex course fulfilled.

Conclusion: The present study provides that the artificial reflex could complete injured facial muscle contract to take replace of the facial nerve and restore function of injured facial muscle. This method may be a new strategy for facial peripheral paralysis patients.