gms | German Medical Science

81st Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

12.05. - 16.05.2010, Wiesbaden

Inverted papilloma of the nose and paranasal sinuses: retrospective review of 110 cases

Meeting Abstract

  • corresponding author presenting/speaker Christian Cordes - Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University Kiel, Germany
  • Natella Velixon - Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University Kiel, Germany
  • Stefan Gottschlich - Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University Kiel, Germany
  • Markus Hoffmann - Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University Kiel, Germany
  • Petra Ambrosch - Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University Kiel, Germany

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. 81st Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. Wiesbaden, 12.-16.05.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. Doc10hno092

doi: 10.3205/10hno092, urn:nbn:de:0183-10hno0923

Published: July 6, 2010

© 2010 Cordes et al.
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Outline

Text

An inverted papilloma (IP) is a rare benign tumor of the nasal cavity and paranasal sinuses, which can be locally aggressive and has a tendency to recur and a malignant potential.

In this clinical study, 110 patients (age 15 to 82 years (53.4+13.6)) with the diagnosis IP, which were treated from 1990 to 2000 in our department, were analysed retrospectively to define sex, tumor location and method of treatment in correlation to the recurrence free time and postoperative complication rate.

Involvement of the maxillary sinus was observed in 50% of patients. In 90% the IP was located unilaterally. In all cases primary surgical resection of IP was performed. A recurrence occurred in 18.2% of patients. No statistically significant correlation was observed between sex, tumor location and treatment technique correlated to the recurrence free time. Association with malignancy was observed in 3.6% of cases. Patients treated with an extranasal technique or a combination of endo- and extranasal technique showed statistically significant more sinusitis (p=0.014), nasal crusting (p=0.027) and paresthesia of the skin (p=0.01). The latest recurrence occurred 8 years after resection of the IP.

We conclude that, if the tumor has adequate size and location, primary endoscopic technique should be preferred to extranasal techniques because of less postoperative complication rates. Regarding the recurrence free interval, the endonasal technique provides no disadvantage compared to other techniques. A longterm postoperative follow up should be performed due to the risk of late recurrences.