Article
Local botulinum toxin therapy for treatment of tardive tongue dyskinesia
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Published: | July 8, 2008 |
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Tardive dyskinesia (TD) is a severe side effect of antipsychotic medication. Recommended treatments for TD are not always successful and can be associated with additional adverse reactions. We report a case of a 28 years old man suffering from a severe TD of the tongue secondary to an antipsychotic medication five years ago. The pronounced tongue protrusion produced mainly speech problems and psychosocial problems. Several treatment options including clozapine, aripiprazole, ziprasidone, tiapride and clonazepam failed to improve the symptoms. Bilateral Injection of 50 U of botulinum toxin A (Dysport®, 200 U/ml) into genioglossal muscle dramatically improved tongue protrusion within three days. The effect lasted for four month and was successfully repeated afterwards. The local botulinum toxin injection is a modern and well-tolerated treatment option for the TD of the tongue.