Article
Localisation and Histology of Malignant ENT-Tumours in Women
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Published: | July 8, 2008 |
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Introduction: A lot of data can be found in literature due malignant diseases in the ENT-area. Hardly any data is available regarding malignant tumours in women.
Method: The files of 146 female were evaluated from 1991 until 2007. Aim of this study was the characterisation of malignant tumours in women. The scope of this research comprised data collection concerning demographics, type and size of tumour, stage, therapy, course of the disease. Objective parameters were collected such as laboratory parameters, height, weight.
Findings: At the time of diagnosis the women had average age of 59. The period of time between noticing first symptoms and secured diagnosis was 11 months. Scrutiny of the files of the 146 female patients revealed that 62 of those women (42%) were smokers. At the time of examination a number of 55 women (38%) were still smoking and consuming alcohol, whilst only 12 of these patients (8%) were actually addicted to alcohol. The analysis of tumour localisation showed 31 (21%) tumours of oropharynx, followed by cancer of the salivary gland in case of 24 patients (16%), 17 patients (12%) had cancer growth in the larynx or on the skin, 15 women (10%) had cancer in the oral cavity. From a histological point of view 85 female patients (58%) had a squamous cell carcinoma. The analysis of salivary gland tumours showed an adenocarcinoma in 11 cases (7.5%).
Conclusion: A remarkable occurrence of tumours in the oropharynx and salivary gland of female patients was noticed. All women were in good general condition and lab-chemical parameters were in most cases within the normal range at the time of diagnosis. In consideration of the localisation of tumours found in women, there is a difference to male tumour-population where predominantly laryngeal carcinoma are seen.