gms | German Medical Science

76th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

04.05. - 08.05.2005, Erfurt

Lymph Node Metastasis of Chordoma

Meeting Abstract

  • corresponding author Uta Wörtgen - HNO, Universitätsklinikum, Essen
  • Friedrich Otterbach - Pathologie, Universitätsklinikum, Essen
  • Jan Peter Thomas - HNO, Universitätsklinikum, Essen
  • Götz Lehnerdt - HNO, Universitätsklinikum, Essen

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 76. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.. Erfurt, 04.-08.05.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc05hno255

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/hno2005/05hno121.shtml

Published: September 22, 2005

© 2005 Wörtgen et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

Chordomas are rare neoplasms taking their origin from the remains of embryonal notochordal cells along the spinal axis. They often occur at the cranial base and are characterized by slow locally invasive tumor progression. The incidence of lymph node metastasis is rare.

We report the case of a 36 year old patient with progressive cervical tumors appearing two years after the primary diagnosis of a chordoma at the basal region of the skull area. After initial surgical resection followed by a protons/photons radiotherapy the chordoma reoccured at the cervical spine half a year ago.

The first time we saw the patient the ultrasound showed multiple pathologic cervical lymph nodes with an average size of 23 mm.The magnet resonance imaging additionally revealed necrosis within these lymph nodes.

Therefore the patient underwent bilateral neck dissection. Histologic examination confirmed the diagnosis of two left and one right lymph node metastasis of the known chordoma.

In conclusion the detection of increased lymph nodes in a patient with the diagnosis of a chordoma can be a sign for a metastatic disease of the tumor even though this is rarely seen.


References

1.
El-Mofty SK, Kyriakos M. Soft Tissue and Bone Lesions. In: Douglas R, Gnepp MD, editors. Diagnostic Surgical Pathology of the Head and the Neck. Saunders; 1996
2.
Graf K, Fisch U. Chordome. In: Berendes J, Link R, Zöllner F, editors. Hals- Nasen- Ohrenheilkunde in Praxis und Klinik. Stuttgart: Georg Thieme; 1979
3.
Campbell WM, McDonald TJ, Unni KK, et al. Nasal and paranasal presentations of chordomas. Laryngoskope. 1980;90:612-8.
4.
Walter WP, Landis SK, Bromley CM, et al. Immunhistochemical distinction of classic and chondroid chordomas. Mod Pathol. 1991;4:661-6.