gms | German Medical Science

G-I-N Conference 2012

Guidelines International Network

22.08 - 25.08.2012, Berlin

French Microbiology Laboratories Practices concerning Antibiotic Therapy and Prevention of Antimicrobial Resistance

Meeting Abstract

  • V. Vernet-Garnier - Haute Autorité de Santé, Saint Denis, France
  • R. Bataillon - CHU de Reims, Reims, France
  • T. Le Ludec - CHU de Reims, Reims, France
  • A. Durocher - CHU de Reims, Reims, France

Guidelines International Network. G-I-N Conference 2012. Berlin, 22.-25.08.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. DocP159

DOI: 10.3205/12gin271, URN: urn:nbn:de:0183-12gin2713

Published: July 10, 2012

© 2012 Vernet-Garnier et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Background: HAS promoted guidelines on prevention of bacterial resistance and quality of microbiology labs.

Objectives: Analysis of implementation of guidelines.

Methods: Checklists for organisation and practices of 227 representative hospital labs.

Results: Survey of bacterial resistance was made in 95% of labs with internal quality control (85% of public, 64% of private labs -p = 0.001), evaluation of procedures in 57% of general, 84% of private labs (p = 0.012). A basic service was maintained in 85% of labs. Delay for giving the antibiotic susceptibilities was lower than 36 h in 33% of public , 52% of private labs (p = 0.038). There was a information system in 88% of public, 75% of private labs (p = 0.006), a liaison with the pharmacy in 78% of public, 63% of private labs (p = 0.043). There was an epidemiological surveillance (87%), and an alert system (93%) mostly by computer in public hospitals or by phone in private labs (56%) (p = 0.003). Results on resistance rates were submitted to the committee for the prevention of hospital infection (93%) or of anti-infectives (71%), to the clinical departments in 50% of public, 75% of private hospitals (p = 0.022). Bacterial resistances were compared with antibiotic consumptions in 45% of general, 61% of university, 34% of private hospitals (p = 0.026).

Conclusions: Efforts have to be performed in internal quality procedures and communication about bacterial resistances to the institutional committees and clinical departments.