gms | German Medical Science

104th DOG Annual Meeting

21. - 24.09.2006, Berlin

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Relationship between trace elements and retinopathy of prematurity

Meeting Abstract

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  • H. Yang - Department of Ophthalmology, Tongji Hospital, Affiliated Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan, China
  • Y. Ding - Department of Ophthalmology, Tongji Hospital, Affiliated Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan, China
  • L. Chen - Department of Ophthalmology, Tongji Hospital, Affiliated Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan, China

Deutsche Ophthalmologische Gesellschaft e.V.. 104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft (DOG). Berlin, 21.-24.09.2006. Düsseldorf, Köln: German Medical Science; 2006. Doc06dogP246

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dog2006/06dog768.shtml

Published: September 18, 2006

© 2006 Yang et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Objective

To observe the metabolism change of trace elements in the blood of preterm infants and infants who suffer from retinopathy of prematurity.

Methods

We selected 30 preterm infants who had potential high risk factors for ROP as the study group and 18 normal infants as the control group. We measured the content of trace elements (such as Mg, Cu, Zn, Mn, Se) in their serum by spectrophotometry.

Results

The contents of Zn, Cu and Se in the serum of the 30 patients were (0.75±0.22) mg/l, (0.41±0.20) mg/l and (134.07±71.57)×10-3 mg/l, respectively, but (0.55±0.12) mg/l, (0.65±0.194) mg/l and (202.92±44.71)×10-3 mg/l in the 18 control subjects. The contents of Cu and Se are significantly lower in the study group than in the control group (P<0.01), while the content of Zn in patients serum is significantly higher (P<0.01). And there are similar result between the infants that suffer from ROP and the control group (P<0.01). The difference of Mn and Mg content in the serum of the two groups was not statistically significant.

Conclusions

The contents of Cu and Se in preterm infants who had a high risk of ROP are lower than those of the control group. Among them the contents of Cu and Se in the ROP infants are also much lower while the content of Zn is much higher. This may play a role for the development of ROP.