Article
Multifocal chorioretinitis and optic neuritis caused by Bartonella henselae
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Authors
Published: | September 22, 2004 |
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Outline
Text
Objective
The etiopathology of posterior uveitis remains often despite meticulous diagnostic unclear. One of the possible pathogens is Bartonella henselae, a recently characterized and classified gramnegative rod.
Methods
A 41-year-old healthy female was referred because of recurrent posterior uveitis and optic neuritis OD of unknown cause. The initial event occured one year ago and was treated in another clinic with oral steroids and clindamycin. The visual acuity increaced from 0,05 to 1,0. An etiology could not be found. The serology for borrelia, lues and toxoplasma was negative. A tuberculosis and sarcoidosis could be excluded. At the initial presentation in our clinic the patient complained of an acute loss of vision OD.
Results
Ophthalmoscopy disclosed a mild temporal optic disc edema and multiple, subretinal white choroidal infiltrates at the posterior pole. A significant delay of the P100-response in VECP-testing confirmed the clinical diagnosis of an optic neuritis. The indirect fluorescend antibody test revealed positive IgG and negative IgM for Bartonella henselae. After therapy with oral steroids visual acuity increased from 0,5 to 0,8.
Conclusions
The classical manifestation of cat-scratch disease in the posterior segment is a neuroretinitis or a multifocal chorioretinitis. In these cases Bartonella h. should also be considered as a possible etiopathogen. Our case shows that a recurrent optic neuritis may play a significant role in visual loss in cat-scratch disease