gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Ropivacain: preemptive analgesia in vitreoretinal surgery

Meeting Abstract

  • corresponding author N. Kristin - University Eye Hospital, Ludwig-Maximilians-University, Munich
  • S. Hierneis - University Eye Hospital, Ludwig-Maximilians-University, Munich
  • C.-L. Schönfeld - University Eye Hospital, Ludwig-Maximilians-University, Munich
  • A. Kampik - University Eye Hospital, Ludwig-Maximilians-University, Munich

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogP 178

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Kristin et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




Vitrectomies are performed either in general anesthesia or in local anesthesia. Postoperative pain is expected to be less in patients with local anesthesia because of prolonged action of the local anesthetic. Preemptive analgesia is based on the idea that analgesia initiated before a nociceptive event will be more effective than analgesia commenced afterwards. We investigated the efficacy of additional pre- or postoperative local anesthetic to general anesthesia.


60 patients scheduled for pars plana vitrectomy without buckling were enrolled in the study. All patients underwent general anesthesia, 45 with preoperative (group A-C) and 15 with postoperative local anesthesia (group D). Additional local anesthetic was Ropivacain 1%: Group A: 1 ml; group B 3 ml und group C and D 5 ml. Subjective postoperative pain was determined using the visual analogue scale.


The additional preoperative application of local anesthesia resulted in less pain in group C than additional postoperative application in group D (p < 0.013). There were no differences among group A, B and D.


It is suggested that local anesthesia with at least 5 ml Ropivacain 1% preoperatively in addition to general anesthesia provides the best comfort for the patient in the postoperative period after vitreoretinal surgery.