gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Reproducibility of measuring the thickness of peripapillary retinal nerve fiber layer with optical coherence tomography and retinal thickness analyzer

Meeting Abstract

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  • corresponding author R. Krist - Universitäts-Augenklinik Mainz, Mainz
  • E. M. Hoffmann - Universitäts-Augenklinik Mainz, Mainz
  • O. Schwenn - Augenklinik Bürgerhospital, Frankfurt

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogP 136

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Krist et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




The measurement of the peripapillary retinal nerve fiber layer (RNFL) thickness can make a contribution for example in the early diagnosis of glaucoma. Object of the present study was to compare the intra- and interexaminer reproducibility of the measurements with optical coherence tomography (OCT) and retinal thickness analyzer (RTA).


There were enrolled 22 eyes of 22 patients. Successively the 2 examiners (EMH, RK) performed three measurements of the peripapillary RNFL with RTA and OCT. Evaluated was the coefficient of correlation (Spearman) of the single measurements of one examiner (intraexaminer) and also between both examiners (interexaminer).


The measurements with RTA proved to be moderately or well reproducible with coefficients of correlation between 0,59 to 0,76 (EMH) and 0,55 to 0,79 (RK). Generally indicating a smaller range the measurements of the OCT showed better intraexaminer reproducibility with coefficients of correlation between 0,82 and 0,91 (EMH) and 0,88 up to 0,91 (RK). Also the reproducibility of the measurements done with OCT between different examiners were superior to RTA (coefficient of correlation 0,91 against 0,84).


Both with RTA and OCT you can measure peripapillary RNFL thickness reproducibly. Showing a smaller range of the measurements the OCT is superior to the RTA in this point.