Article
Asymmetric visual field loss and retrobulbar blood-flow velocities in primary open-angle glaucoma
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Authors
Published: | September 22, 2004 |
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Outline
Text
Objective
To investigate retrobulbar blood flow velocities in patients with asymmetric glaucomatous visual field loss.
Methods
Twenty-five patients with primary open-angle glaucoma and asymmetric visual field loss (mean deviation >6dB) were included in this prospective study. Blood flow velocities (peak systolic velocity PSV and end-diastolic velocitiy EDV) and resistive indices of the ophthalmic artery, central retinal artery (CRA) and nasal and temporal posterior ciliary arteries were measured by means of colour Doppler imaging.
Results
Mean deviation of eyes with more severe glaucomatous visual field loss was -17.5dB versus -5.5dB (p<0.0001). Intraocular pressure and perfusion pressure were not significantly different between eyes. The EDV of the central retinal artery was significant decreased in eyes with more severe glaucomatous field loss (2.24±0.46 cm/s versus 2.53±0.49 cm/s, p<0.041). None of the data of the other retrobulbar vessels were significantly different.
Conclusions
Patients with asymmetric glaucomatous visual field loss exhibit asymmetric end-diastolic velocities of the CRA in primary open-angle glaucoma. The posterior ciliary arteries did not show any significant differences between eyes.