gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Article

Send article

In vitro experiments to evaluation of optimal edges of lens optics for prevention of posterior capsular opacification

Meeting Abstract

Search Medline for

  • corresponding author A. Wildeck - Department of Ophthalmology, University Hospital of Berlin (Charité), Berlin; Eye Center Alt-Moabit, Berlin
  • A. Sänger - Department of Ophthalmology, University Hospital of Berlin (Charité), Berlin; Eye Center Alt-Moabit, Berlin
  • M. Tetz - Department of Ophthalmology, University Hospital of Berlin (Charité), Berlin; Eye Center Alt-Moabit, Berlin

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogP 074

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dog2004/04dog565.shtml

Published: September 22, 2004

© 2004 Wildeck et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Objective

To develop a new method for the evaluation of the optic edge design of intraocular lenses.

Methods

PMMA-lenses were specially manufactured with 11 different edge designs. Each lens design was evaluated using the programm EPCO 2000. Also its ability to stop cell growth was observed by placing each lens into cell culture and observing the cell growth over a period of 18 days on average.

Results

Out of the 11 different edge design groups only the first 3 groups with the sharpest edge design were able to prevent the growth of lens epithelial cells into the visual axis of the lens. The edge design which effectively stops cell growth is characterized by an area above the edge of 13,5μm2 at the most.

Conclusions

Results showed that the edge design of intraocular lenses plays an important role for the prevention of posterior capsule opacifiaction and also that there exists a specific optic edge design which is most effective for this prevention.