gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Antimetabolites and other concepts for wound healing modulation in glaucoma surgery : prospective studies

Meeting Abstract

  • corresponding author F. Grehn - Universitäts-Augenklinik Würzburg
  • G. Schlunck - Universitäts-Augenklinik Würzburg
  • T. Meyer-ter-Vehn - Universitäts-Augenklinik Würzburg
  • G. Karasheva - Universitäts-Augenklinik Würzburg
  • I. Wimmer - Universitäts-Augenklinik Würzburg

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSO.02.06

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Grehn et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



The use of the antimetabolites Mitomycin C (MMC) and 5-Fluorouracil (5-FU) is well established for complicated glaucomas in prospective randomized trials. The principal use in every glaucoma operation, however, is not generally accepted. The comparison between MMC and 5-FU shows equal efficacy in the preliminary data of a prospective study. New concepts of wound healing modulation are being investigated with an antibody against Transforming Growth Factor β-2 (TGFβ2) in a prospective randomized study. Further concepts of wound healing modulation are being tested in prospective studies.