gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Visual outcome and ultrastructure study of macular hole surgery with membrane-blue®-assited peeling of the internal limiting membrane

Meeting Abstract

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  • corresponding author S. Synek - Department of Ophthalmology and Optometry, Masaryk University, Brno, Czech Republic
  • L. Pác - Department of Anatomy, Masaryk University, Brno, Czech Republic

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSO.01.14

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Synek et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




To evaluate the anatomical and visual outcome in macular hole patients who underwent surgery with membrane-blue®-assisted internal limiting membrane (ILM) peeling.


After pars plana vitrectomy, in some eyes membrane-blue®-assisted removal of the internal limiting membrane was performed. Samples of membranes were examined by transmissive electron microscopy (TEM).


The mean follow-up was 12 months (range 9 -36 months). The median preoperative visual acuity was 6/36 (0, 16) and increased to 6/12 (0,5) postoperatively. All eyes had a better final visual acuity. Membrane-blue®-assisted peeling is more comfortable and safe. The TEM samples showed an ultrastructure of ILM. We found no big differences between samples with Membrane-Blue®-assisted peeling or without.


These findings indicate that membrane-blue®-assisted removal of internal limiting membrane is safe and made surgery much easier.