gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

First experiences with semifluorinated alkanes as endotamponade in complicated retinal surgery

Meeting Abstract

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  • corresponding author D. Sandner - Klinik mit Poliklinik für Augenheilkunde am Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden
  • T. Maulhardt - Klinik mit Poliklinik für Augenheilkunde am Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden
  • K. Engelmann - Klinik mit Poliklinik für Augenheilkunde am Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSO.01.08

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dog2004/04dog410.shtml

Published: September 22, 2004

© 2004 Sandner et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

Objective

When pure perfluorohexyloctane (F6H8) is used as tamponade agent in retinal surgery, intraocular irritations and chronic hypotonia are observable after a treatment period of 3 weeks to 3 months. This study focusses on the effect of "heavy silicone oil", a mixture of perfluorohexyloctane (F6H8) and silicone oil that combines the gravity of F6H8 and the high viscosity of silicone oil, as a tamponade agent in patients with complex detachment of the inferior retina after conventional silicon oil tamponade.

Methods

Between 10/03 -03/04, 16 patients (average age 66 yrs; 32 - 83 yrs) received a pars plana vitrectomy followed by exchange of the previous tamponade agent against heavy silicone oil (F6H8/silicone oil mixture). All patients had 1-4 previous surgical interventions (average 1.7) and showed persisting detachment of the inferior retina under conventional silicone oil tamponade. After 3 months resting time the heavy silicone oil tamponade is to be removed and the eyes examined for anatomic success and/or intraocular complications. Up to now the "heavy silicone oil" tamponade was removed in 5 of 16 patients after an average resting time of 110 d (72 - 130 d).

Results

In contrast to perfluorohexyloctane (F6H8) as sole tamponade "heavy silicone oil", the mixture of F6H8 with silicone oil, caused only mild intraocular irritations or limited retrolental deposits. After removal of the tamponade agent recurrent ablatio retinae was observed in 2 of 5 eyes.

Conclusions

Subsequently to unsuccessful conventional silicone oil tamponade, a long-term tamponade with "heavy silicone oil" can facilitate reattachment of the inferior retina in case of persisting amotio retinae. The lacking inflammatory reaction of the treated eye is advantageous compared to pure F6H8. Besides the evaluation of long-term effects on vision, the percentage of patients with a stable retinal attachment after removal of the tamponade agent remains to be determined.