gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

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Follow-up after tamponade with perfluorohexyloctane (F6H8) as treatment for retinal detachment

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  • corresponding author H. Nitzsche - Klinik mit Poliklinik für Augenheilkunde am Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden
  • D. Sander - Klinik mit Poliklinik für Augenheilkunde am Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden
  • T. Maulhardt - Klinik mit Poliklinik für Augenheilkunde am Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden
  • K. Engelmann - Klinik mit Poliklinik für Augenheilkunde am Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSO.01.05

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dog2004/04dog407.shtml

Published: September 22, 2004

© 2004 Nitzsche et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Objective

The treatment of non-attached inferior retina after conventional silicone oil tamponade with perfluorohexyloctane (F6H8) seems to be an improved therapeutic approach. Own experience revealed severe complications after 3 months resting time of the F6H8. This study demonstrates short-term effects of F6H8 as tamponade for 3 weeks.

Methods

Casuistry. 12 patients (average age 61,5±21,5, 41 - 82 yrs) with complicated retinal detachment and previous surgical intervention (average 2,25 surgical treatments; 0 - 5 surgeries) were treated with pars plana vitrectomy and exchange of silicone oil against F6H8 as tamponade agent. Removal of the tamponade agent was performed 24 d post surgery (17 - 27 d).

Results

All patients showed intraocular irritations, such as endothelial and retrolental precipitations or severe capsular fibrosis in case of pseudophacic eyes. Removal of the tamponade agent occurred without complications in all patients after an average of 24 d. Only minor retinal precipitations were seen. 7 of 12 patients experienced re-ablatio retinae shortly after removal of F6H8 with detachment of the superior or central retina. Severe cases of hypotonia as seen after 3 months treatment with F6H8 were not observed in this study. In comparison, patients who underwent panretinal laser coagulation prior to F6H8 treatment showed no detachment and retinal precipitates and only minor irritations.

Conclusions

F6H8 as a heavy liquid tamponade agent should only be administered after careful selection of patients. It seems - in our opinion - not suitable for routine treatment of complex retinal detachment. It remains to be investigated, if changes of the blood-retinal-barrier or the retinal contact area, e.g. after laser coagulation, have an influence on the therapeutic outcome.