gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Histological effects of prostaglandine analogues on the iris and conjunctiva following long-term therapy before glaucoma surgery

Meeting Abstract

  • corresponding author I. Liehneová - Departement of Ophthalmology, Regional Hospital Teplice/CZ
  • A. Cech - Departement of Ophthalmology, Regional Hospital Teplice/CZ
  • J. Sach - Institute of Pathology, 3rd Medical Faculty, Teaching Hospital, Prague, Czech Republic
  • H. Stanicová - Institute of Pathology, Regional Hospital Teplice/CZ

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogSA.08.07

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Liehneová et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




To determine whether long-term therapy of prostaglandine analogues caused proliferative or degenerative effects on the iris and conjunctiva of patients with glaucoma.


14 patients planning filtering surgery for uncontrolled IOP caused by POAG were randomized to receive topical prostaglandine analogues / n= 7 / or alternative medication before surgery / n=7 /. The specimen of iris and conjunctiva tissue was obtained from each patient during surgery and was subjected to histological evaluation.


No degenerative or pathological changes were seen in the prostaglandine analogues treated irides despite that macroscopically colour of irides was changed. The features of stromal inflammation were detected / 4 out of 7 patients / in the histological sections of conjunctiva.