gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

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Optic disc topography and retinal nerve fiber layer thickness in glaucoma suspects and patients with manifest glaucoma: a comparison between optical coherence tomography (OCT) and scanning-laser tomography (HRT)

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  • corresponding author W. Goebel - Department of Ophthalmology, University of Wuerzburg
  • G. Karasheva - Department of Ophthalmology, University of Wuerzburg

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogDO.06.05

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dog2004/04dog055.shtml

Published: September 22, 2004

© 2004 Goebel et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Objective

Scanning Laser Tomography with the Heidelberg Retina Tomograph (HRT) is well established in the analysis and follow-up of the optic disc configuration in glaucoma patients. With the Stratus OCT a new instrument for optic disc topography, based on optical coherence tomography has become available. Therefore, we compared optic disc analysis and retinal nerve fiber layer thickness measurements by OCT with HRT as the "gold standard".

Methods

41 eyes of 21 patients with suspected or manifest glaucoma were included in the study. In each eye optic disc analysis was performed with the Stratus OCT (3 repeat measurements) and the HRT (3 repeat measurements). In addition, a peripapillary scan of the retinal nerve fiber layer was done with the Stratus OCT (3 repeat measurements). The central 30 degree visual field was documented with the Octopus 101 perimeter, program G2. The mean visual field defect (MD) was analysed. Neuroretinal rim area (RA), cup/disc area ratio (CDA) and mean retinal nerve fiber layer thickness (RNFL) were compared between OCT and HRT.

Results

The RA measured 1.190±0.42 mm2 (range 0.30-2.00 mm2) with the OCT and 1.48±0.37 mm2 (range 0.79-2.49 mm2) with the HRT. The CDA was 0.53±0.20 (range 0.06-0.92) for the OCT and 0.42±0.16 (range 0.05-0.74) for the HRT. RA and CDA correlated well between both imaging techniques with correlation coefficients of r=0.85, p<0.0001 and r=0.74, p<0.0001 respectively. The RNFL thickness correlated less between OCT and HRT with a correlation coefficient of r=0.54, p=0.0003. The Correlation between both imaging techniques on the one hand and visual field MD on the other was relatively poor (correlation coefficient range 0.37-0.43).

Conclusions

In our sample of 41 eyes with and without glaucomatous field damage OCT and HRT proved to be equally suitable for the analysis of optic disc topography.