gms | German Medical Science

22nd International Congress of German Ophthalmic Surgeons

18. to 21.06.2009, Nürnberg

Collagen cross linking and laser surgery

Meeting Abstract

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  • A.J. Kanellopoulos - NYU Medical Scool, Clinical Associate Professor of Ophthalmology, Athen, Griechenland

22. Internationaler Kongress der Deutschen Ophthalmochirurgen. Nürnberg, 18.-21.06.2009. Düsseldorf: German Medical Science GMS Publishing House; 2009. Doc09docH 1.6

doi: 10.3205/09doc003, urn:nbn:de:0183-09doc0036

Published: July 9, 2009

© 2009 Kanellopoulos.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Purpose: To introduce our experience in employing CXL in conjunction with laser cornea surgery

Methods: Summary data of multiple studies will be presented: in utilizing topography-guided PRK in a therapeutic manner z after or even simultaneous with CXL, in post-LASIK ectasia and primary keratoconus in over 500 cases and follow-up up to 6 years.

Results: The laser treatment-when employed conservatively-appears to add significantly to the "normalization" of the cornea surface, and the improvement in UCVA and BSCVA.. As a result cornea transplantation was avoided in most cases as means of treatment. Our experience additionally suggests synergistic effect when the two modalities (laser and CXL) were combined. Minor complications included post-op haze and delayed epithelial healing. There were minimal cases registered that failed to stabilize.

Conclusion: Laser surgery and CXL may be combined in order to visually rehabilitate eyes with progressive ectasia following LASIK and keratoconus. larger studies and longer follow-up are necessary to validate these data.