gms | German Medical Science

German Congress of Orthopedic and Trauma Surgery (DKOU 2017)

24.10. - 27.10.2017, Berlin

Role of growth factors in osteonecrosis of the femoral head

Meeting Abstract

  • presenting/speaker Thomas Pufe - Universitätsklinik Aachen, Institut für Anatomie und Zellbiologie, Aachen, Germany
  • Rainer Beckmann - Universitätsklinik Aachen, Institut für Anatomie und Zellbiologie, Aachen, Germany
  • Mersedeh Tohidnezhad - Universitätsklinik Aachen, Institut für Anatomie und Zellbiologie, Aachen, Germany
  • Athanassios Fragoulis - Universitätsklinik Aachen, Institut für Anatomie und Zellbiologie, Aachen, Germany
  • Holger Jahr - RWTH Aachen University, Dept. of Orthopaedic Surgery, Aachen, Germany
  • Wolf Drescher - Rummelsberg hospital, Dept. of orthopedic surgery, Schwarzenbruck, Germany

Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017). Berlin, 24.-27.10.2017. Düsseldorf: German Medical Science GMS Publishing House; 2017. DocIN14-201

doi: 10.3205/17dkou033, urn:nbn:de:0183-17dkou0334

Published: October 23, 2017

© 2017 Pufe et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

Text

Objectives: Osteonecrosis of the femoral head leads to a failure of the hip joint in severe ARCO stages. Own results and recent publications revealed that growth factors are participated in aetiology and pathology of osteonecrosis of the femoral head. Aim of the present talk is to give an overview about the different growth factors and their role in osteonecrosis of the femoral head.

Methods: Most of the investigations were performed by using ELISA, immunohistochemical and real time RT PCR techniques.

Results and Conclusion: Several investigations indicate that there is a link between growth factors and aetiology and pathology of osteonecrosis of the femoral head. Future studies have to reveal the importance of growth factors in osteonecrosis of the femoral head.