gms | German Medical Science

27th German Cancer Congress Berlin 2006

German Cancer Society (Frankfurt/M.)

22. - 26.03.2006, Berlin

Treatment of Locally Invasive Thyroid Cancer

Meeting Abstract

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  • corresponding author presenting/speaker Rudolf Roka - 1.Chirurgische Abteilung, KA Rudolfstiftung, Wien, Österreich
  • Michael Hermann - Chirurgische Abteilung, Kaiserin Elisabeth Spital, Wien
  • Michael Pramhas - 1.Chirurgische Abteilung, KA Rudolfstiftung, Wien

27. Deutscher Krebskongress. Berlin, 22.-26.03.2006. Düsseldorf, Köln: German Medical Science; 2006. DocPO245

The electronic version of this article is the complete one and can be found online at:

Published: March 20, 2006

© 2006 Roka et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Introduction: Prognosis in differentiated thyroid cancer is fairly good. However, this is not true for locally advanced cancers. Radical surgery may not be achieved and patients die from local complications. In a retrospective study we try to establish therapeutic guidelines by defining risk groups.

Patients and Methods: 96 patients with locally advanced tumors underwent surgery with curative intent. Surgical procedures were classified into: curative shaving resections (defined as R0, R1), incomplete shaving resections (defined as R2), resection of exclusive muscle infiltration and major visceral resections.

Results: Overall survival was 53% in papillary thyroid cancer compared to 35% in follicular thyroid cancer (p=0,001). In case of organ invasion, prolonged survival was only seen after radical resection (defined as R0 or R1 resection). Radioiodine treatment increased survival in patients with papillary thyroid cancer after nonradical resection.

Conclusion: Resections with gross residual disease were associated with poor outcome. Therefore massive invasion demands complete cervicovisceral resection, whenever possible. For only superficial invasion, shaving resections of the larynx or trachea are recommended because of lower morbidity and similar survival rates compared to en bloc resections.