Article
Long-term results of endovascular treatment of intracranial aneurysms
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Published: | April 28, 2011 |
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Objective: Mid-term results of endovascular treatment of intracranial aneurysms yielded promising results. Our study focuses on the long-term results in terms of efficiency, recurrence rates and overall complications over a period of 10 years.
Methods: We included 91 patients with intracranial aneurysms (52 with ruptured and 39 with unruptured aneurysms). A total of 119 aneurysms were treated by endovascular coiling from 1992 to 1998. Endpoints according to treatment-related morbidity and mortality (Glasgow Outcome Scale) were obtained from 75 patients as well as radiological data on occlusion rates could be obtained from 70 surviving patients after a mean follow-up of 10 years.
Results: Treatment-related mortality was found in 6.7% (5/75), four of these patients had a ruptured aneurysm. Treatment related morbidity was 18.6%, in 8 patients with unruptured (11.4%) and in 6 patients with ruptured aneurysms (8.5%). A primary total occlusion of the lesion could be achieved in 66.3% (61/92). In 47.8% (44/92) of the aneurysms a recurrence was noted after an average of 4.2 years. Twenty-six of them required at least one further embolization. Recurrences were more often detected in large aneurysms (p < 0.05). A re-recurrence was seen in 61% (16/26) after a successful re-treatment.
Conclusions: The comparatively high mortality rate reflects the fact that initially poor grade patients were also treated by endovascular methods. The long-term stability of endovascular treatment seems to be less reliable than clipping. Especially large aneurysms need to be observed meticulously in the long-term. Perhaps the additional use of stents and/or flow-diverters will help to lower the recurrence rates in the endovascular field.