Article
Awake operation of glioma patients using intraoperative MRI control
Gliomoperationen bei wachen Patienten mit intraoperativer MRT-Kontrolle
Search Medline for
Authors
Published: | April 11, 2007 |
---|
Outline
Text
Objective: Brain surgery in local anaesthesia is used for resection of brain tumors adjacent to eloquent brain areas. The aim of surgery is to maximize the extent of resection and minimize postoperative neurological deficits. Therefore, intraoperative MRI combined with neuronavigation was used for resection control in patients who underwent awake surgery.
Methods: From December 2005 to October 2006, n=12 Patients (9 male and 3 female) with glial tumors (WHO Grade II-IV) adjacent to eloquent brain areas underwent surgery under local anaesthesia. Prior to operation, the patients were tested neuropsychologically. Intraoperative MRI (1,5 Tesla) and constant neuropsychological and neurophysiological monitoring were performed.
Results: In seven patients all MR-morphologically detectable tumor tissue was resected without any neurological deterioration. In four patients a small remnant of tumor was left with constant neurology, and in one patient occurred new neurological deficits despite subtotal resection.
Conclusions: Awake surgery combined with intraoperative MRI-control and neuronavigation is a safe approach to maximize the extent of tumor removal and to minimize the resultant neurological deficits in the treatment of glioma involving eloquent cortex areas