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55. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e. V. (DGNC)
1. Joint Meeting mit der Ungarischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

25. bis 28.04.2004, Köln

Enhancement of the benefits of intraoperative electrophysiological recordings during framebased stereotactic surgeries by customized signal analysis

Verbesserte Nutzung elektrophysiologischer Ableitungen während rahmenbasierter stereotaktischer Eingriffe durch den Einsatz maßgefertigter Analysesoftware

Meeting Abstract

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  • corresponding author Kerstin Menne - Institut für Signalverarbeitung und Prozessrechentechnik, Universität zu Lübeck, Seelandstr. 1a, 23569 Lübeck
  • U. G. Hofmann - Institut für Signalverarbeitung und Prozessrechentechnik, Universität zu Lübeck, Seelandstr. 1a, 23569 Lübeck

Deutsche Gesellschaft für Neurochirurgie. Ungarische Gesellschaft für Neurochirurgie. 55. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 1. Joint Meeting mit der Ungarischen Gesellschaft für Neurochirurgie. Köln, 25.-28.04.2004. Düsseldorf, Köln: German Medical Science; 2004. DocMI.03.02

The electronic version of this article is the complete one and can be found online at:

Published: April 23, 2004

© 2004 Menne et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




We will present results of the BMBF project navEgate whose overall objective is the enhancement of target point accuracy during framebased stereotactic surgeries for the implantation of deep brain stimulators. At the Institute for Signalprocessing in Lübeck we especially focus on the development of online visualization and signal analysis tools that gain the utmost information from intraoperatively recorded electrophysiological signals.


The software is integrated into our 32-channel data acquisition system (50 kHz per channel), developed according to DIN EN 60601-1-4. The algorithms are tested on the basis of in situ recorded data from patients suffering from Parkinson Syndrome or Dystonia, kindly provided by some neurosurgeons, and on the basis of realistically simulated data. We chose features like wavelet coefficients, Fourier coefficients, correlations and spike rates to distinguish one brain region from the other. In addition, these features get stored related to an AC-PC based anatomical reference coordinate system in our database system navEbase. The complete navEgate system consists of the following components. A newly developed probe (IMM) enables synchronous recording from 32 channels, linearly or helically arranged on one shaft. The design allows to gain a neural signal depth profile from about the first 1 cm of probe length. The feed of the probe is controlled by a computerized microdrive (Thomas Recording). Preoperative planning and image-based navigation is performed within the new iPlan software (Brainlab). The penetration depth of the probe is there presented online on top of the patient image material.


Our system is designed to assist novice as well as experienced neurosurgeons and to provide a great tool for medical research. The integrated database system enables the surgeon to compare current intraoperative data at a certain location against signal features to be expected at this point, thus providing additional feedback about the assumed position. Clinical trials of the complete system are expected for spring 2004.