gms | German Medical Science

131. Kongress der Deutschen Gesellschaft für Chirurgie

Deutsche Gesellschaft für Chirurgie

25.03. - 28.03.2014, Berlin

Quality of life and neurological tests measurements in patients after minimal-invasive mitral valve surgery

Meeting Abstract

  • Inna Kammerer - Klinikum Ludwigshafen, Herzchirurgie, Ludwigshafen
  • Armin Vomend - Klinikum Ludwigshafen, Herzchirurgie, Ludwigshafen
  • Arndt-H. Kiessling - Universitätsklinik der Johann-Wolfgang-Goethe Universität, Herzchirurgie, Frankfurt am Main
  • Falk-Udo Sack - Klinikum Ludwigshafen, Herzchirurgie, Ludwigshafen

Deutsche Gesellschaft für Chirurgie. 131. Kongress der Deutschen Gesellschaft für Chirurgie. Berlin, 25.-28.03.2014. Düsseldorf: German Medical Science GMS Publishing House; 2014. Doc14dgch531

doi: 10.3205/14dgch531, urn:nbn:de:0183-14dgch5315

Published: March 21, 2014

© 2014 Kammerer et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Objective: Clinical benefit of mitral valve reconstruction (MVR) is well documented, but comparative data of long term follow-up (> 12months period) in postoperative quality of life (QoL) and mental power are missing. We hypothesised that mitral valve reconstruction with isolated mitral valve disease have neuropsychological benefits in 1-years follow-up.

Methods: Since 2011 40 patients (mean 60years, 75% male) after non-emergent MVR were enrolled. In a prospective trial, psychological measurements like SF-36 with 8 scaled scores about physical and mental health, depressive analysis (BDI), neuropsychological tests like Mini-Mental test (KMS), Trial A, B tests and 6-minute-walk (6MWT) for exercise tolerance was assessed before (n=38), 9days (n=34) and 12months (n=19) after surgical intervention.

Results: In a paired t-test model correcting for physical function SF-36 headings were detected significant lower scores, especially in period before vs. 9 days after the operation (p>0,001) and vs. after 12 months (p>0,001) without significances in mental power scores during the time. The 6-minute-walk measure decreased to hospital discharge date: 516m preOP vs. 438m postOP (p>0,038) vs. 526m 12months later (n.s.). Significant differences showed Part B in postoperatively period: 88min pre OP vs. 111min post OP (p>0,001) vs. 100min 12 months after OP (p>0,01).

Conclusions: The differences of QoL and neurological testing in patients with MVR in 1-years period outcome showed significant improvement as well in physical fitness (6MWT) as in SF-36 measures.