gms | German Medical Science

129. Kongress der Deutschen Gesellschaft für Chirurgie

Deutsche Gesellschaft für Chirurgie

24.04. - 27.04.2012, Berlin

CT-MIBI-SPECT image fusion detects abnormal parathyroid adenomas in patients with goitre

Meeting Abstract

  • Gerd Wimmer - Universitätsklinik Innsbruck, Chirurgie, Innsbruck
  • Michael Sieb - Universitätsklinik Innsbruck, Chirurgie, Innsbruck
  • Thomas Resch - Universitätsklinik Innsbruck, Chirurgie, Innsbruck
  • Kurt Stromberger - Universitätsklinik Innsbruck, Chirurgie, Innsbruck
  • Johann Pratschke - Universitätsklinik Innsbruck, Chirurgie, Innsbruck
  • Rupert Prommegger - Universitätsklinik Innsbruck, Chirurgie, Innsbruck

Deutsche Gesellschaft für Chirurgie. 129. Kongress der Deutschen Gesellschaft für Chirurgie. Berlin, 24.-27.04.2012. Düsseldorf: German Medical Science GMS Publishing House; 2012. Doc12dgch262

doi: 10.3205/12dgch262, urn:nbn:de:0183-12dgch2624

Published: April 23, 2012

© 2012 Wimmer et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.



Introduction: The aim of this study was to evaluate whether CT-MIBI-SPECT image fusion is superior to MIBI-SPECT and CT alone in detecting abnormal parathyroid glands in patients with hyperparathyroidism and concomittant goitre.

Materials and methods: CT-MIBI-SPECT image fusion was performed in 40 patients who had to be operated on for hyperparathyroidism and concomittant goitre. CT-MIBI-SPECT image fusion results were compared with CT and MIBI-SPECT alone. The predicted positions were correlated with intraoperative findings.

Results: CT-MIBI-SPECT image fusion was able to predict the exact position of all abnormal glands per patient in 75% of patients, whereas CT alone succeeded in 45% and MIBI-SPECT alone in 50%. In all patients simultaneous thyroidectomy had to be performed. Overall accuracy for CT-MIBI-SPECT image fusion was 92,0%, for CT alone 84,0%, for MIBI-SPECT 83,0%.

Conclusion: This study shows that CT-MIBI-SPECT image fusion is superior to CT or MIBI-SPECT alone for preoperative localization of abnormal parathyroid glands in patients with hyperparathyroidism and goitre.