gms | German Medical Science


Figure 2: To analyze the effect of IP10 on mTORC1 activation in vivo, mouse femoral arteries were injured as described and mTOR expression was investigated. Expression of mTOR protein was significantly upregulated 14 days after vascular injury in WT mice. However, CXCR3-deficiency nearly completely inhibited this effect. (Mean ± SEM , n=8, *=p<0.05 compared with WT)