Figure 1: Relative increases in neural activity associated with traumatic accident memories compared to negative non-traumatic autobiographical memories in patient AF non-PTSD) and patient RK (acute PTSD). The local maxima of areas of statistically significant relative increases in neural activity are superimposed on sections of the T1-weighted high resolution MR template provided by SPM2 to depict the functional anatomy of the activations and their relationship to the underlying structural anatomy. Standard stereotactic coordinates of the pixels with the local maximum of activation were determined within areas of significant relative changes in neural activity associated with the two different memory conditions. These local maxima were anatomically localized by reference to a standard stereotactic atlas [42]. The figure focuses on medial temporal lobe activations associated with traumatic memory. The exact coordinates of the local maxima within the areas of activation and their t-statistics are shown in Table 1a.