gms | German Medical Science

Figure

Figure 1: Multimodal retinal imaging of Vogt-Koyanagi-Harada disease of both eyes at presentation. (a, b) Color fundus photograph shows multifocal subretinal detachments (SRD) involving the posterior pole of the right eye and the peripapillary area of both eyes. (c, d) Fluorescein angiography late frames show areas of pinpoint hyperfluorescent leaks of the retinal pigment epithelium with multifocal dye pooling underneath the SRD. (e, f) Indocyanine green angiography (ICGA) frames show persistent multiple hypofluorescent lesions, better seen in the late phases of the examination. (g) Enhanced-depth imaging optical coherence tomography (EDI-OCT) scan of the right eye shows increased subfoveal choroidal thickness (712 µm, white rhombus) and a bacillary detachment (white asterisk) associated with fibrin-like subretinal hyperreflective material (yellow arrow). (h) EDI-OCT of the left eye shows increased subfoveal choroidal thickness (750 µm, white rhombus) and extrafoveal subretinal accumulation of fluid (white asterisk). (i, j) OCT angiography of the choriocapillaris (4.5x4.5 mm) of both eyes shows multiple flow void spots (yellow arrowheads) at the posterior pole that correlate with the hypofluorescent lesions detected on ICGA.