Figure 6: Time course of CD-31 positive vessels in cold water-treated animals (controls; blue bars), as well as in animals treated with EPO500 45 min (light grey), EPO500 6 hrs (intermediate grey) or EPO2,500 45 min (dark grey) (A). Mean ± SEM; *p<0.05 vs. controls; n=7/group. Staining for CD31 at day 7 after burn in a control animal (B), as well as in an animal receiving EPO500 45 min (C), EPO500 6 hrs (D), and EPO2,500 45 min (D) respectively. Positive vessels indicating vessel density are represented by brown staining, which is almost only seen in EPO-treated animals (arrow heads). Scale bar 30 µm.