gms | German Medical Science

GMS Current Posters in Otorhinolaryngology - Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNOKHC)

ISSN 1865-1038

Histopathological pattern of nasopharyngeal mass in adults

Poster Onkologie

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  • corresponding author Khaled Ali - Sohag University Hospital, Sohag, Egypt
  • Mostafa El-Taher - Sohag University Hospital, Sohag, Egypt
  • Zaki Aref - South Valley University Hospital, Qena, Egypt

GMS Curr Posters Otorhinolaryngol Head Neck Surg 2017;13:Doc245

doi: 10.3205/cpo001799, urn:nbn:de:0183-cpo0017992

Published: April 26, 2017

© 2017 Ali et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at



Introduction: Nasopharyngeal mass resembles a confounding problem in adults because of the increased fear of malignancy with age. Histopathological pattern of nasopharyngeal lesions varies greatly from common benign lesions such as hyperplastic lymphoid tissue and benign nasopharyngeal cysts to malignant diseases such as lymphoma and nasopharyngeal carcinoma.

Methods: We conducted a prospective study that included all adult patients presented to our tertiary referral hospital with a nasopharyngeal mass in 2 years period from October 2014 to September 2016. Blind punch biopsy was taken for cases clinically suspicious for having nasopharyngeal neoplasm. Histopathological findings were analyzed as regard demographic data and clinical presentation.

Results: A total of 100 patients (54 males and 46 females) were included. Patients' age ranged between 16 and 76 years (mean SD = 38.7 16.7 years). The most commonly detected pathological lesion was hyperplastic lymphoid tissue hyperplasia (60%). Malignant lesions constituted 38% of the study population (10% squamous cell carcinoma, 14 % undifferentiated carcinoma, and 14% malignant lymphoma). In addition, benign nasopharyngeal cysts were diagnosed in 2% of cases.

Conclusion: Benign lesions are more commonly detected in the nasopharynx in adult population particularly hyperplastic lymphoid tissue. Histopathological examination of nasopharyngeal mass is very essential to rule out malignancy which is not uncommon.

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