gms | German Medical Science

International Conference on SARS - one year after the (first) outbreak

08. - 11.05.2004, Lübeck

An seroepidemiological study on SARS in different populations of Guangdong Province

Poster

  • corresponding author Hui Li - Centers for Disease Control and Prevention of Guangdong Province
  • Ji-cheng Huang - Centers for Disease Control and Prevention of Guangdong Province
  • Ling Fang - Centers for Disease Control and Prevention of Guangdong Province
  • Jie Li - Centers for Disease Control and Prevention of Guangdong Province
  • Zhuo-yue Wang - Centers for Disease Control and Prevention of Guangdong Province
  • Jin-yan Lin - Centers for Disease Control and Prevention of Guangdong Province
  • Xiao-ping Xu - Centers for Disease Control and Prevention of Guangdong Province
  • Li-mei Diao - Centers for Disease Control and Prevention of Guangdong Province
  • Jin Yan - Centers for Disease Control and Prevention of Guangdong Province
  • Wang-li Zhang - Centers for Disease Control and Prevention of Guangdong Province
  • Ping Huang - Centers for Disease Control and Prevention of Guangdong Province
  • Wei Li - Centers for Disease Control and Prevention of Guangdong Province
  • Xin-ge Yan - Centers for Disease Control and Prevention of Guangdong Province
  • Huan-ying Zheng - Centers for Disease Control and Prevention of Guangdong Province
  • Hong-jian Xu - Centers for Disease Control and Prevention of Guangdong Province
  • Feng Deng - Centers for Disease Control and Prevention of Guangdong Province

International Conference on SARS - one year after the (first) outbreak. Lübeck, 08.-11.05.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04sarsP2.01

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/sars2004/04sars104.shtml

Veröffentlicht: 26. Mai 2004

© 2004 Li et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Background: The first SARS case was found in Foshan, a small city of Guangdong Province. A total of 1512 cases were clinically confirmed till Jun 15,2003 in Guangdong Province.

Objective: To estimate the prevalence of SARS, explore epidemic scale and characteristic of SARS, evaluate the risk of exposure to SARS CoV.

Methodology: A total of 7708 cases were divided into 4 groups including 127 clinically confirmed patients, 1133 close contacts, 5964 general healthy population and 484 animal traders. SARS CoV-IgG was screened by ELISA at first and then confirmed by IFA. The titer of positive samples had been detected by ELISA.

Result: 66.9% samples were positive in patients group, whereas 0.88% in close contacts group, and 13.4% in animal trades group. No positive case was found in general healthy population. Positive rate among patients with contact history was higher than that without contact history significantly(p=0.000). The incidence among people with contact histoty was 6.7%(78/1164) including 9.85% in female and 4.43% in male and positive rate of antibody was 7.22%(84/1164). The positive rate of antibody among health workers was lower than that among relatives and friends of SARS patients. The positive rate among animal traders was higher than other non-SARS population, whereas that among civet and wild boar salesmen was up to 58.9%.The positive rate by ELISA in children was 2.06% higher than that in whole general healthy population(0.96%). The coincidence between IFA and ELISA was 69.7%. The titer in different groups was different.

Conclusion: The positive rate of antibody in whole people is still very low. Another outbreak should be paid attention. Close contacts have high risk. Wild animals maybe the source of SARS. There maybe exit some cross-reaction antibody to SARS CoV in Some people.