Artikel
Application of nitric oxide in complex treatment of burn´s ischemia of conjuntiva (clinical research)
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Autoren
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Pavel Makarov
- Moscow/Russia
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O. Kvasha
- Moscow/Russia
| Veröffentlicht: | 18. Juni 2008 |
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Gliederung
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Purpose: Development of optimum algorithm of non-surgical treatment of burn's ischemia of conjunctiva with application of Nitric oxide (NO-therapy).
Methods: 27 patients with burn's ischemia of conjunctiva were observed. The complex treatment included traditional non-surgical treatment and 2–5 courses of NO-therapy with concentration 300 particle per million 1 time in day. The medical air-plasma device "Plason" was used as a source of a NO-containing gas flow (NO-GF).
Results: The optimum circuit of therapy of the patients with burn's ischemia of conjunctiva is developed. Restoration of microcirculation in a zone of ischemia of conjunctiva and the recovery has come at 44.4 % of the patients in early terms after a trauma. The medical effect was within first three days from a beginning of treatment.
Conclusion: The complex treatment of burn's ischemia of conjunctiva with application of NO-therapy promotes faster reduction of an inflammation, reduction of edema, faster restoration of blood circulation in a damaged conjunctiva and in zone of regional limbal vessels, closing of epithelial defect of cornea, prevents an opportunity of corneal ulceration. The mode of application of NO-therapy (number of influences) is established individually depending on degree of a burn, terms after a trauma, dynamics of restoration of microcirculation and individual features.
