gms | German Medical Science

21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem
8. Symposium der International Society of Ocular Trauma

Deutsche Gesellschaft für Retinologie
International Society of Ocular Trauma

19.06. - 22.06.2008, Würzburg

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Retinal pigment epithelial rip in a twelve-years-old girl after intravitreal injection of ranibizumab for choroidal neovascularisation

Meeting Abstract

Suche in Medline nach

  • Isabel Oberacher-Velten - Regensburg/Germany
  • K. Hufendiek - Regensburg/Germany
  • C. Framme - Regensburg/Germany
  • H. Helbig - Regensburg/Germany

Retinologische Gesellschaft. International Society of Ocular Trauma. 21. Jahrestagung der Retinologischen Gesellschaft gemeinsam mit dem 8. Symposium der International Society of Ocular Trauma. Würzburg, 19.-22.06.2008. Düsseldorf: German Medical Science GMS Publishing House; 2008. DocISOTRG2008V130

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/rg2008/08rg131.shtml

Veröffentlicht: 18. Juni 2008

© 2008 Oberacher-Velten et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

Text

Background: Retinal pigment epithelial rips in children are very unusual and have not been further reported so far.

Case report: A twelve-years-old girl suffered from inner ear deafness and retinopathy presumably due to asymptomatic intrauterine varizella-zoster-infection. When she presented first with visual loss in the OD, a minimal classic CNV was diagnosed. At that time, no signs of retinal pigment epithelial rip were found. After written informed consent was obtained from her parents, the child was treated by three consecutive intravitreal injections with ranibizumab 0.05 mg. Three weeks after the first injection, a retinal pigment epithelial rip was found. The two following injections were continued as predetermined. Visual acuity improved from 20/400 to 20/50. Optical coherence tomography showed significant reduction of intraretinal and subretinal fluid.

Conclusions: A retinal pigment epithelial rip which is very unusual for children developed three weeks after intravitreal injection of ranibizumab. Improvement of visual acuity however occurred after two further injections as previously reported in adults.