gms | German Medical Science

Fourth International Symposium and Workshops: Objective Measures in Cochlear Implants

Medical University of Hannover

01.06. bis 04.06.2005, Hannover

Effects of Adaptation on the Electrically Evoked Compound Action Potential

Meeting Abstract

  • corresponding author C.J. Brown - University of Iowa, Iowa City
  • K. Schmidt-Clay - University of Iowa, Iowa City
  • M. Hay-McCutcheon - Indiana University, Indianapolis
  • C. Etler - University of Iowa, Iowa City
  • P. Abbas - University of Iowa, Iowa City

Medical University of Hannover, Department of Otolaryngology. Fourth International Symposium and Workshops: Objective Measures in Cochlear Implants. Hannover, 01.-04.06.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc05omci022

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Veröffentlicht: 31. Mai 2005

© 2005 Brown et al.
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This presentation will describe results of three separate studies that all focus on defining the effects of adaptation on the electrically evoked compound action potential as recorded in Nucleus cochlear implant users. The goal of these studies was to characterize how increases in stimulation rate affect the ECAP and to compare electrophysiologic measures of peripheral neural adaptation with psychophysical measures of threshold, temporal integration and word recognition. Results of these studies demonstrate that: (1) for many subjects considerable amounts of adaptation occur even for stimulation rates as low as 80 Hz, (2) the amount of adaptation occurring within a five minute period is not significantly correlated with word recognition, and (3) electrophysiologic measures of adaptation are not correlated with psychophysical measures of temporal integration. Initial data will also be presented describing effects of adaptation on the ECAP as measured from subjects implanted with the Nucleus RP8 device for stimulation rates between 10 and 500 Hz. Implications of these results on clinical practice and considerations for further investigation will be discussed.