gms | German Medical Science

54. Jahrestagung der Norddeutschen Orthopädenvereinigung e. V.

Norddeutsche Orthopädenvereinigung

16.06. bis 18.06.2005, Hamburg

Biomechanical properties of cartilage repair tissue after different surgical treatments in a sheep model

Meeting Abstract

  • corresponding author J. Kunow - Institut für Orthopädie, Labor für Biomechanik, Lübeck
  • P. Behrens - Lübeck
  • J. Gille - Lübeck
  • W. Köller - Lübeck
  • P. Stomberg - Lübeck
  • B. Kurz - Kiel
  • M. Russlies - Lübeck

Norddeutsche Orthopädenvereinigung. 54. Jahrestagung der Norddeutschen Orthopädenvereinigung e.V.. Hamburg, 16.-18.06.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc05novFJW2

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/nov2005/05nov049.shtml

Veröffentlicht: 13. Juni 2005

© 2005 Kunow et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Introduction

The aim of this study was to evaluate the biomechanical quality of cartilage and repair tissue in a sheep's knee. Two standardized 7 mm defects were created on the medial femoral condyle and patella groove (n=30). These were treated with five different cartilage repair procedures and examined one year later.

Material and Methods

The different groups were: (1) a cell-seeded collagen type I/III matrix (Chondro-Gide®); (2) a cell-seeded collagen type II matrix; (3) microfracture; (4) microfracture and a collagen type I/III matrix (Chondro-Gide®); (5) microfracture and a collagen type II matrix. All matrices were sutured or glued to the defect. As controls we used equivalent cartilage defects in the contralateral knee. Indentation tests were performed over 35 s to calculate the "25s-creep-index" . The elastic modulus was determined on the basis of the instantaneous indentation within the initial 0,25 s.

Results

The untreated defects were filled with less repair tissue than the treated ones. Generally, the repair tissues revealed a lower biomechanical quality compared to native cartilage. There were no significant differences between the treated groups.

Conclusion

In this animal study, none of the induced repair tissues was biomechanically comparable to genuine articular cartilage.