gms | German Medical Science

28. Wissenschaftlicher Kongress der Deutschen Hochdruckliga

24. bis 27.11.2004, Hannover

Type 2 Diabetes mellitus: Treatment of Hypertension and microalbuminuria 1997 - 2003: Typ-2-Diabetes mellitus: Behandlung von Hypertonie und Mikroalbuminurie 1997 - 2003

Meeting Abstract (Hypertonie 2004)

Suche in Medline nach

  • presenting/speaker E. Jungmann - St. Vinzenz Hospital Rheda-Wiedenbrück (Rehda-Wiedenbrück, D)
  • J. Bolle - St. Vinzenz Hospital Rheda-Wiedenbrück (Rehda-Wiedenbrück, D)
  • C. Schmitz - St. Vinzenz Hospital Rheda-Wiedenbrück (Rehda-Wiedenbrück, D)
  • U. Snelting - St. Vinzenz Hospital Rheda-Wiedenbrück (Rehda-Wiedenbrück, D)

Hypertonie 2004. 28. Wissenschaftlicher Kongress der Deutschen Hochdruckliga. Hannover, 24.-27.11.2004. Düsseldorf, Köln: German Medical Science; 2005. Doc04hochP76

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/hoch2004/04hoch076.shtml

Veröffentlicht: 10. August 2005

© 2005 Jungmann et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

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Introduction: The beneficial effects of tight blood pressure control on microalbumiuria and other microangiopathic outcome parameters in type 2 diabetes mellitus are beyond doubt. Therefore, there was hope that in clinical practice, the control of hypertension in type 2 diabetic patients might also improve.

Methods: Potential changes in the prevalence of microalbuminuria or in the effectiveness of antihypertensive treatment were examined in all insulin-naive patients referred to our clinic in 1997 - 2003 for initiation of insulin treatment.

Subjects: 365 patients' files were examined.

Results: Mean age decreased from 64 +/- 1 (average + SEM) in 1997 to 62 +/- 1 years in 2003, duration of diabetes from 9 +/- 1 to 6 +/- 1 years, body mass index increased from 29.2 +/- 0.3 to 30.3 +/- 0.5 kg/m²,. The rate of increased urinary albumin excretion dropped from 59 % to 42 % (all p < 0.05). The rate of antihypertensive treatment increased from 61 % to 75% (p < 0.01). Systolic blood pressure decreased from 136 +/- 2 mmHg to 133 +/- 2 mmHg (p < 0.05). Diastolic blood pressure and creatinine levels in serum were unchanged. The prevalence of diabetic neuropathy decreased from 69 % to 53 % (p < 0.05).

Conclusions: Corresponding to our hope that the control of blood pressure might have improved since 1997, there was a clear-cut tendency to a more persistent approach to the treatment of hypertension between 1997 and 2003 in our type 2 diabetic patients. Therefore, there appears to be a realistic chance that more strict treatment targets for hypertensive and/or microalbuminuric patients with type 2 diabetes mellitus will at last be implemented into treatment regimen in clinical practice.