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Can be flexible esophagogastroduodenoscopy useful for diagnosis of early laryngeal and hypoharyngeal carcinomas?
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Veröffentlicht: | 4. April 2012 |
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Introduction: Laryngohypopharyngeal neoplastic diseases are frequently diagnosed at advanced stage. Laryngeal and hypopharyngeal photos (LHP) performed during routine esophagogastroduodenoscopy (EGD) were used for diagnosis of laryngeal and hypopharyngeal diseases.
Methods: In this pilot prospective three standard LHPs (larynx, right and left piriform sinus) were recorded during all EGD. LHPs were subsequently independently evaluated for presence of neoplastic and non-neoplastic lesions by gastroenterologist (GE) and otorhinolaryngologist (ORL) and clinical examination was performed if indicated by ORL. Inclusion criteria were age 18-80 years and informed consent of patient.
Results: Total number of 930 patients (males 479, females 451, mean age 56 (SD±15,5) years) were included. 19(2%) patients were excluded because of low quality of LHPs. Based on LHPs, GE suspected patology in 6,8% (62/911) and ORL suspected patology in 59,9% (545/911) of patients. Clinical examination was performed by ORL in 3,9%.
The most frequent finding was reflux laryngitis (55,9%). Laryngeal spinocellular carcinoma was found and histologically confirmed in 4 (0,4%) patients (all four males, mean age 60 years, all recognized both by GE and ORL), benign lesion in 43 (4,7%) patients. There were no associations of reflux laryngitis for sex, body mass index, presence of endoscopic esofagitis, smoking, alcohol, dysphagia, tec.
Conclusion: Laryngeal and hypopharyngeal photos were feasible in 98% of patients coming to routine EGD. We have found patology in almost 60% of patients. The most frequent finding was reflux laryngitis. Although no early carcinoma was detected, we conclude that routine endoscopic examination of laryngeal and hypopharyngeal region could be beneficial for the patient.