gms | German Medical Science

82. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

01.06. - 05.06.2011, Freiburg

Flat electrode array for an endosteal stimulation of the cochlear nerve (endosteal electrodes)

Meeting Abstract

  • Raquel Manrique - Clinica Univ. Facultad Medicina, ORL, Pamplona, Spanien
  • S. Picciafuoco - Clinica Univ. Facultad Medicina, ORL, Pamplona, Spanien
  • J. Gracia - School of Engineering of the University of Navarre, Pamplona, Spanien
  • I. Ayerdi Olaizola - School of Engineering of the University of Navarre, Pamplona, Spanien
  • M. Manrique - Clinica Univ. Facultad Medicina, ORL, Pamplona, Spanien

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 82. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Freiburg i. Br., 01.-05.06.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. Doc11hnod405

doi: 10.3205/11hnod405, urn:nbn:de:0183-11hnod4051

Veröffentlicht: 19. April 2011

© 2011 Manrique et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Introduction: In order to treat patients with bilateral profound sensorineural hearing losses, Cochlear Implants (CI) have been historically used with electrode arrays placed intraluminally in the cochlea. The development of new technologies enables the creation of flat electrode arrays (FEA), with a minimum thickness of 80 µm. These FEA could be used to stimulate the auditory nerve from an endosteal position in the lateral wall of the cochlea, placed longitudinally along the basal turn. The technique could be performed atraumatically, enabling a selective treatment of sensorineural hearing losses in high frequencies and treat tinnitus.

Materials and Methods: The EE has a cochlear insertion zone 0.5–0.7 mm wide. This EE version has an active area, 10 mm. long, which contains platinum film deposition on a 80 µm thick flexible substrate made of PDMS polymer. It is implanted in a first series of 10 human temporal bones (HT) and then in 6 ears of Macacas fascicularis. The morphological findings are analyzed via the histological processing of the HT and the hearing preservation via the ABR.

Results: The histological analysis of the human temporal bones implanted show that the spiral ligament has been completely conserved after an 8mm deep insertion of the FEA. Also, functional results in monkeys show that is possible to preserve a normal hearing function after an endosteal FEA implantation.