Artikel
Sentinel-Node-Biopsy for cutaneous meanoma of the head and neck – an analysis of 50 cases
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Autoren
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Matthias Scheich
- Univ. Dept. of ENT, Wuerzburg, Germany
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Alessandro Relic
- ENT-Hospital Hietzing, Vienna, Austria
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Michael Kreissl
- Univ. Dept. of Nuclearmedicine, Wuerzburg, Germany
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Hans-Ullrich Völker
- Univ. Dept. of Pathology, Wuerzburg, Germany
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Jürgen Becker
- Univ. Dept. of Dermatology, Wuerzburg, Germany
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Rudolf Hagen
- Univ. Dept. of ENT, Wuerzburg, Germany
| Veröffentlicht: | 22. Juli 2009 |
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Gliederung
Text
Introduction: Cutaneous melanoma of the head and neck are aggressive tumors with poor prognosis according to tumor thickness. We performed sentinel lymphnode biopsy (SLNB) in 50 patients (thickness 1.0–10 mm; Clark Level III-V) from 3/03 to 10/08.
Methods: Radioactive labelled microalbumine particles were injected around the tumor/scar. Injection was followed by an early dynamic as well as a late static scintigraphy. SLNB was performed on the next day under general anaesthesia using a gamma-probe.
Results: In 50 patients we resected 1–7 sentinel nodes (total 114). In three cases we could not detect a SLN. 30 patients (60%) had intraparotideal nodes. 6 patients showed melanoma-metastases in 1–3 SLNs, in one patient we detected a metastasis beside a negative SLN. In all 7 patients we performed a neck dissection and parotidectomy. In 13% of the patients the therapy strategy had to be changed because of the positive SLN, whereas 87% of the patients had not to undergo a neck dissection or parotidectomy.
Conclusion: SLNB is a safe procedure to precise staging and therapy in cutaneous melanoma of the head and neck. It is necessary to have good experience in neck and parotid surgery as well as to have a good interdisciplinary team to conduct this procedure.
