gms | German Medical Science

78. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

16.05. - 20.05.2007, München

Nasal complications involving the use of a calcitonin nasal spray for osteoporosis

Meeting Abstract

  • corresponding author Angelos Chatziavramidis - General Hospital Giannitsa, Giannitsa, Greece
  • Dimosthenis Gennadiou - General Hospital Giannitsa, Giannitsa, Greece
  • Ioannis Delis - General Hospital Giannitsa, Giannitsa, Greece
  • Dimitrios Derwisis - General Hospital Giannitsa, Giannitsa, Greece

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. 78th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. Munich, 16.-20.05.2007. Düsseldorf, Köln: German Medical Science; 2007. Doc07hno103

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/hno2007/07hno103.shtml

Veröffentlicht: 8. August 2007

© 2007 Chatziavramidis et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Calcitonin in the form of nasal spray is widely used for the treatment of postmenopausal osteoporosis as well as for other skeletal diseases. Generally it has low percentage of side-effects that are usually mild and of local character. We present two cases of postmenopausal women with osteoporosis being treated with intranasal calcitonin in which a septum perforation and a septum-concha synechiae led the patients to our ENT department. These lesions after clinical and laboratory examination were attributed to the use of intranasal calcitonin. A questionnaire submitted to a greater number (n=238) of women undergoing treatment with calcitonin, as well as nasal cytology showed inflammatory changes of nasal mucosa in those patients who gave a positive answer for intranasal side-effects. We review the literature on nasal calcitonin use and discuss the possible mechanisms causing local side-effects.

(Literature from the corresponding author)