gms | German Medical Science

76. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.

04.05. - 08.05.2005, Erfurt

Aetiology of chronic rhinosinusitis – retrospective analysis of 1156 cases

Meeting Abstract

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  • corresponding author Stefan Tesche - Department of Oto-,Rhino-,Laryngology, Head and Neck-Surgery, Medical School Hamburg, Hamburg
  • Christoph Sagowski - Department of Oto-,Rhino-,Laryngology, Head and Neck-Surgery, Medical School Hamburg, Hamburg
  • Thomas Grundmann - Department of Oto-,Rhino-,Laryngology, Head and Neck-Surgery, Medical School Hamburg, Hamburg

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 76. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.. Erfurt, 04.-08.05.2005. Düsseldorf, Köln: German Medical Science; 2005. Doc05hno101

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/hno2005/05hno212.shtml

Veröffentlicht: 22. September 2005

© 2005 Tesche et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielf&aauml;ltigt, verbreitet und &oauml;ffentlich zug&aauml;nglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Introduction: The aetiology of chronic rhinosinusitis (CRS) seems to change. The incidence of allergies has dramatically risen; there is a better understanding of the inflammatory mechanisms in CRS. Superantigens and fungi are supposed to play an important role in the development of CRS.

Patients and Methods: We retrospectively analysed the medical records of 1156 patients (females 41%, males 59%), who underwent sinus surgery in our clinic for CRS. The mean age was 44 years.

Results: The histological examination revealed in 74,1% an eosinophilic, in 25,9% a neutrophilic type of inflammation. Eosinophilic CRS was correlated with an increased risk of recurrence. Links to an allergy were found in 43,1%, an intolerance to aspirin (AI) was seen in 5,4% and in 1,4% we found an aspergillosis (non-invasive). In 50% the CRS remained unclassified!

9,7% of all patients suffered from asthma. In this subgroup allergies and AI were seen in 94,6%. A recurrence of CRS was seen in 35,5%. Here the CRS remained unclassified in 48%!

Conclusion: The eosinophilic CRS is predominant. In patients with asthma and CRS allergies and AI have to be taken into the diagnostic and therapeutic considerations. The huge number of unclassified patients with recurrence of CRS stresses the importance of last years` scientific work.