Artikel
Granular cell tumor (Abrikossoff tumor) of the solid palatum
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Veröffentlicht: | 22. September 2005 |
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Gliederung
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The granular cell tumor, that was first described by Abrikossof in 1926, is a rare benign tumor of neuronal histiogenesis. Nevertheless cases of malignant granular cell tumor occur in less than 2% of reported cases. Any location of the body can be affected. In the head and neck area the esophagus, the tongue and the larynx are by far the most common location. In a newborn the granular cell tumor appears as epulis connatalis on the maxillary and mandibular gingiva. Granular cell tumors appear in a range of patients from children to the elderly, with the mean usually in middle adult life.
In this case we describe a never reported granular cell tumor of the solid palatum. Microscopically the tumor is specified as indistinct benign, placed subepithelial. The tumor cells show uncertain cell boarders and an ample amount of granular eosinophil cytoplasma.
Granular cell tumors are surgically excised. A rhabdomyosarkoma and a squamous cell carcinoma must be excluded. On the basis of the rare malignant transformation we prefer a continuous follow up of the patient.