gms | German Medical Science

MAINZ//2011: 56. GMDS-Jahrestagung und 6. DGEpi-Jahrestagung

Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V.
Deutsche Gesellschaft für Epidemiologie e. V.

26. - 29.09.2011 in Mainz

Artikel

Artikel empfehlen

Depressive Symptoms in Latest Life: Incidence, Persistence and Risk Factors - Results of the Leipzig Longitudinal Study of the Aged (LEILA 75+)

Meeting Abstract

Suche in Medline nach

  • Melanie Luppa - Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig
  • Claudia Sikorski - Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig
  • Tobias Luck - Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig
  • Siegfried Weyerer - Central Institute of Mental Health, Mannheim
  • Hans-Helmut König - Department of Medical Sociology and Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg
  • Steffi G. Riedel-Heller - Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig

Mainz//2011. 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi). Mainz, 26.-29.09.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. Doc11gmds231

doi: 10.3205/11gmds231, urn:nbn:de:0183-11gmds2311

Veröffentlicht: 20. September 2011

© 2011 Luppa et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

Text

Aims: With regard to the increasing importance of depressive symptoms in the eld-erly population, the present study aims to determine the incidence, risk factors and the course of depression in latest-life within a German population-based, representative study of individuals aged 75 years and older.

Methods: As part of the Leipzig Longitudinal Study of the Aged (LEILA 75+), a population-based sample of 1,265 individuals aged 75 years and older were interviewed on socio-demographic, clinical, and psychometric variables. Depressive symptoms were assessed using the CES-D (Center of Epidemiologic Studies Depression scale; cut-off score >=23); cognitive state was assessed using the Mini-Mental Status Examination. Predictors of depressive symptoms were determined with Cox proportional hazards regression models.

Results: The incidence of depression in the 860 participants without depression at baseline was 34 per 1,000 person-years (95% con-fidence interval 31-37). Female gender, a poor self-rated health status, stroke in the past, risky alcohol consumption, a poor social network, higher number of specialist’s visits, and functional impairment increased the risk of development of depression. The CES-D score at baseline was associated with a 20% increased risk per point increase. During the 8-year follow-up, we observed remission in 55%, an unstable course in 22% and a chronic course in 23% of the participants.

Discussion: Since depressive symptoms are common in oldest age and associated with broad categories of risk factors, late-life depression represents an important public health issue. Employment of comprehensive geriatric assessment to ascertain depressive symptoms and its concomitants could help to improve treatment success.