gms | German Medical Science

MAINZ//2011: 56. GMDS-Jahrestagung und 6. DGEpi-Jahrestagung

Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V.
Deutsche Gesellschaft für Epidemiologie e. V.

26. - 29.09.2011 in Mainz

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Missing, unreplaced teeth predict mortality, particularly cardiovascular mortality

Meeting Abstract

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  • Ines Polzer - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Christian Schwahn - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Robin Haring - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Marcus Dörr - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Henri Wallaschofski - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Thomas Kocher - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Torsten Mundt - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Stefanie Samietz - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Henry Völzke - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald
  • Reiner Biffar - Universitätsmedizin der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald

Mainz//2011. 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi). Mainz, 26.-29.09.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. Doc11gmds166

doi: 10.3205/11gmds166, urn:nbn:de:0183-11gmds1667

Veröffentlicht: 20. September 2011

© 2011 Polzer et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

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Background: An inverse relationship has been reported between an individual’s number of teeth and mortality. Previous research has focused on the systemic inflammatory response to mediate this relationship and, therefore, on the number of remaining or missing teeth as the exposure; but no study has investigated whether the number of missing, unreplaced teeth affects mortality. If dental prostheses have a beneficial effect on mastication and diet, replacing missing teeth may hypothetically decrease mortality risk. Reduced masticatory efficiency can be assumed for individuals having nine or more missing, unreplaced teeth.

Methods and Results: We used data prospectively collected from participants in the population-based Study of Health in Pomerania to examine whether unreplaced teeth were associated with an increased risk of all-cause or cardiovascular mortality. 188 out of 1803 subjects had nine or more unreplaced teeth. During a median follow-up period of 9.9 years, 362 subjects died. Of those, 128 died from cardiovascular causes. Having nine or more unreplaced teeth (rate ratio 1.94 adjusted for variables according to directed acyclic graphs: number of remaining teeth [which suspended other potential confounders such as the smoking status], age, sex, education, income, marital status, partnership, and oral health behavior; reference: fewer than nine unreplaced teeth; 95% confidence interval: 1.15-3.25; P=0.013), but not the number of missing teeth itself, was related to cardiovascular mortality.

Conclusions: The masticatory efficiency rather than systemic inflammatory responses mediates the relationship between the number of teeth and mortality. Clinicians have a responsibility to consider individual chewing ability in their nutritional recommendations.