gms | German Medical Science

54. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)

Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie

07. bis 10.09.2009, Essen

Incidence of chronic venous insufficiency and symptoms in the Bonn Vein Study

Meeting Abstract

  • Felizitas Pannier - Department of Dermatology, AZM Maastricht, Maastricht
  • Sabine Hertel - Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen
  • Barbara Hoffmann - Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen
  • Annette Ko - 3Department of Dermatology, Rheinische Friedrich-Wilhelms-University Bonn, Bonn
  • Gabriele Berboth - 3Department of Dermatology, Rheinische Friedrich-Wilhelms-University Bonn, Bonn
  • Karl-Heinz Jöckel - Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen
  • Eberhard Rabe - 3Department of Dermatology, Rheinische Friedrich-Wilhelms-University Bonn, Bonn

Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie. 54. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds). Essen, 07.-10.09.2009. Düsseldorf: German Medical Science GMS Publishing House; 2009. Doc09gmds020

DOI: 10.3205/09gmds020, URN: urn:nbn:de:0183-09gmds0205

Veröffentlicht: 2. September 2009

© 2009 Pannier et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Background: Chronic venous diseases (CVI) are one of the most frequent diseases in populations of industrialized countries, but only a few studies have addressed the burden of disease in the general population. Our study investigates the incidence and symptoms of CVI in the German population.

Material and methods: Data are derived from the Bonn Vein Study, a population-based cohort study (2000-2008) which included 3072 participants between 18 and 79 years, residing in Bonn and two rural adjacent townships. All participants filled in a questionnaire regarding socio-economic status, lifestyle, medical history and quality of life. Trained examiners conducted an interview concerning the phlebological history and performed a clinical examination including a duplex-sonography. Venous diseases were judged by CEAP-classification (including the clinical score evaluating the symptoms of CVI and the disability score). CVI was defined as at least one limb classified between C3 and C6.

Results: Response at follow-up after a mean of 6.6 years was 84.6%. The full cohort included 740 men and 916 women without CVI at baseline. 216 cases of new CVI were diagnosed at follow-up. The incidence was 14% (95%-CI: 11% - 16%) in women and 13% (95%-CI: 11% -16%) in men over a 6.6 year period and increased in higher age groups. The most common symptoms of CVI were the edema (81%); ulcers were found in only 1%. 19% of all incident CVI cases had moderate pain in the legs and 5% had severe pain, requiring analgesics. Disability scoring showed that 60% had asymptomatic legs, 32% had symptomatic legs, but not using medical compression stockings at work, whereas 5% needed compression therapy. 3% were unable to work due to their symptoms.

Discussion: Among the adult population we predict 1,840 new cases of CVI per 100,000 in one year which means a large disease burden for a population of the size of Germany.